Human marrow stromal cells reduce microglial activation to protect motor neurons in a transgenic mouse model of amyotrophic lateral sclerosis. [electronic resource]
- Journal of neuroinflammation Apr 2013
- 52 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1742-2094
10.1186/1742-2094-10-52 doi
Amyotrophic Lateral Sclerosis--therapy Animals Blotting, Western Bone Marrow Cells--physiology Bone Marrow Transplantation--methods Cell Count Cell- and Tissue-Based Therapy Disease Progression Enzyme-Linked Immunosorbent Assay Gene Dosage Humans Immunohistochemistry Macrophage Activation--physiology Mice Mice, Inbred C57BL Mice, Transgenic Microglia--physiology Motor Neurons--physiology Neurons--physiology Spinal Cord--pathology Stromal Cells--physiology Superoxide Dismutase--genetics Superoxide Dismutase-1 Tumor Necrosis Factor-alpha--metabolism