TY - GEN AU - Yang,Qiong AU - Ferrell,James E TI - The Cdk1-APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch SN - 1476-4679 PY - 2013///0625 KW - Animals KW - CDC2 Protein Kinase KW - metabolism KW - Cdc20 Proteins KW - Cell Cycle KW - Cell Cycle Proteins KW - Computational Biology KW - methods KW - Computer Simulation KW - Cyclin A KW - Cyclin B1 KW - Enzyme Activation KW - Enzyme Assays KW - Feedback, Physiological KW - Models, Biological KW - Ovum KW - cytology KW - Phosphorylation KW - Protein Interaction Mapping KW - Protein-Tyrosine Kinases KW - Proteolysis KW - Time Factors KW - Ubiquitination KW - Xenopus Proteins KW - Xenopus laevis N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ncb2737 ER -