TY  - GEN
AU  - Lessene,Guillaume
AU  - Czabotar,Peter E
AU  - Sleebs,Brad E
AU  - Zobel,Kerry
AU  - Lowes,Kym N
AU  - Adams,Jerry M
AU  - Baell,Jonathan B
AU  - Colman,Peter M
AU  - Deshayes,Kurt
AU  - Fairbrother,Wayne J
AU  - Flygare,John A
AU  - Gibbons,Paul
AU  - Kersten,Wilhelmus J A
AU  - Kulasegaram,Sanji
AU  - Moss,Rebecca M
AU  - Parisot,John P
AU  - Smith,Brian J
AU  - Street,Ian P
AU  - Yang,Hong
AU  - Huang,David C S
AU  - Watson,Keith G
TI  - Structure-guided design of a selective BCL-X(L) inhibitor
SN  - 1552-4469
PY  - 2013///0715
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - Benzothiazoles
KW  - chemistry
KW  - Cell Line, Tumor
KW  - Crystallography, X-Ray
KW  - Drug Design
KW  - Drug Screening Assays, Antitumor
KW  - Humans
KW  - Hydrazones
KW  - Kinetics
KW  - Mice
KW  - Models, Chemical
KW  - Myeloid Cell Leukemia Sequence 1 Protein
KW  - Protein Binding
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - genetics
KW  - bcl-X Protein
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nchembio.1246
ER  -