Lessene, Guillaume

Structure-guided design of a selective BCL-X(L) inhibitor. [electronic resource] - Nature chemical biology Jun 2013 - 390-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1552-4469

10.1038/nchembio.1246 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis
Benzothiazoles--chemistry
Cell Line, Tumor
Crystallography, X-Ray
Drug Design
Drug Screening Assays, Antitumor
Humans
Hydrazones--chemistry
Kinetics
Mice
Models, Chemical
Myeloid Cell Leukemia Sequence 1 Protein
Protein Binding
Proto-Oncogene Proteins c-bcl-2--genetics
bcl-X Protein--antagonists & inhibitors