Lessene, Guillaume
Structure-guided design of a selective BCL-X(L) inhibitor. [electronic resource]
- Nature chemical biology Jun 2013
- 390-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1552-4469
10.1038/nchembio.1246 doi
Animals
Antineoplastic Agents--pharmacology
Apoptosis
Benzothiazoles--chemistry
Cell Line, Tumor
Crystallography, X-Ray
Drug Design
Drug Screening Assays, Antitumor
Humans
Hydrazones--chemistry
Kinetics
Mice
Models, Chemical
Myeloid Cell Leukemia Sequence 1 Protein
Protein Binding
Proto-Oncogene Proteins c-bcl-2--genetics
bcl-X Protein--antagonists & inhibitors