TY - GEN AU - Gribble,Susan M AU - Wiseman,Frances K AU - Clayton,Stephen AU - Prigmore,Elena AU - Langley,Elizabeth AU - Yang,Fengtang AU - Maguire,Sean AU - Fu,Beiyuan AU - Rajan,Diana AU - Sheppard,Olivia AU - Scott,Carol AU - Hauser,Heidi AU - Stephens,Philip J AU - Stebbings,Lucy A AU - Ng,Bee Ling AU - Fitzgerald,Tomas AU - Quail,Michael A AU - Banerjee,Ruby AU - Rothkamm,Kai AU - Tybulewicz,Victor L J AU - Fisher,Elizabeth M C AU - Carter,Nigel P TI - Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome SN - 1932-6203 PY - 2013///1022 KW - Animals KW - Chromosomes, Human KW - radiation effects KW - Chromosomes, Human, Pair 21 KW - Comparative Genomic Hybridization KW - Disease Models, Animal KW - Down Syndrome KW - genetics KW - Gamma Rays KW - adverse effects KW - Gene Dosage KW - High-Throughput Nucleotide Sequencing KW - Humans KW - In Situ Hybridization, Fluorescence KW - Male KW - Mice KW - Oligonucleotide Array Sequence Analysis KW - Recombination, Genetic KW - Trisomy N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0060482 ER -