TY - GEN AU - Houde,Martin AU - Jamain,Marc-David AU - Labonté,Julie AU - Desbiens,Louisane AU - Pejler,Gunnar AU - Gurish,Michael AU - Takai,Shinji AU - D'Orléans-Juste,Pedro TI - Pivotal role of mouse mast cell protease 4 in the conversion and pressor properties of Big-endothelin-1 SN - 1521-0103 PY - 2013///0830 KW - Animals KW - Aorta KW - drug effects KW - Carboxypeptidases A KW - biosynthesis KW - Drug Resistance KW - Endothelin-1 KW - analogs & derivatives KW - Gene Expression Regulation, Enzymologic KW - Heart Ventricles KW - Hemodynamics KW - Isoenzymes KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Organ Specificity KW - Peptide Fragments KW - blood KW - Protein Processing, Post-Translational KW - Proteolysis KW - RNA, Messenger KW - metabolism KW - Serine Endopeptidases KW - chemistry KW - Serine Proteinase Inhibitors KW - pharmacology KW - Sulfonamides KW - Thiophenes KW - Thiorphan N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1124/jpet.112.202275 ER -