Shear stress activates extracellular signal-regulated kinase 1/2 via the angiotensin II type 1 receptor. [electronic resource]
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology Aug 2013
- 3008-16 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1530-6860
10.1096/fj.12-222299 doi
Acetophenones--pharmacology Angiotensin II--pharmacology Angiotensin II Type 1 Receptor Blockers--pharmacology Animals CHO Cells Caveolin 1--genetics Cells, Cultured Cricetinae Cricetulus Endothelial Cells--cytology Enzyme Activation--drug effects Enzyme Inhibitors--pharmacology Human Umbilical Vein Endothelial Cells--cytology Humans Immunohistochemistry Losartan--pharmacology Mice Mice, Inbred C57BL Mice, Knockout Mitogen-Activated Protein Kinase 1--metabolism Mitogen-Activated Protein Kinase 3--metabolism Protein Binding--drug effects RNA Interference Receptor, Angiotensin, Type 1--metabolism Stress, Mechanical