Murugaiyan, Jayaseelan <br/><br/>
Benzo[a]pyrene affects Jurkat T cells in the activated state via the antioxidant response element dependent Nrf2 pathway leading to decreased IL-2 secretion and redirecting glutamine metabolism.  [electronic resource] 

 -  Toxicology and applied pharmacology  Jun 2013 
 - 307-16 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1096-0333 
<br/><br/><label>Standard No.: </label>10.1016/j.taap.2013.03.032  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Basic Helix-Loop-Helix Transcription Factors--drug effects<br/>Benzo(a)pyrene--pharmacology<br/>Blotting, Western<br/>Enzyme-Linked Immunosorbent Assay<br/>Glutamine--metabolism<br/>Humans<br/>Interleukin-2--biosynthesis<br/>Jurkat Cells--drug effects<br/>NF-E2-Related Factor 2--physiology<br/>Receptors, Aryl Hydrocarbon--drug effects<br/>Signal Transduction--drug effects