TY - GEN AU - Jimeno,Antonio AU - Weiss,Glen J AU - Miller,Wilson H AU - Gettinger,Scott AU - Eigl,Bernard J C AU - Chang,Anne Lynne S AU - Dunbar,Joi AU - Devens,Shannon AU - Faia,Kerrie AU - Skliris,Georgios AU - Kutok,Jeff AU - Lewis,Karl D AU - Tibes,Raoul AU - Sharfman,William H AU - Ross,Robert W AU - Rudin,Charles M TI - Phase I study of the Hedgehog pathway inhibitor IPI-926 in adult patients with solid tumors SN - 1557-3265 PY - 2013///1216 KW - Adult KW - Aged KW - Aged, 80 and over KW - Alanine Transaminase KW - metabolism KW - Alopecia KW - chemically induced KW - Area Under Curve KW - Aspartate Aminotransferases KW - Dose-Response Relationship, Drug KW - Drug Administration Schedule KW - Fatigue KW - Female KW - Follow-Up Studies KW - Hedgehog Proteins KW - Humans KW - Male KW - Metabolic Clearance Rate KW - Middle Aged KW - Nausea KW - Neoplasms KW - drug therapy KW - Signal Transduction KW - drug effects KW - Spasm KW - Treatment Outcome KW - Veratrum Alkaloids KW - adverse effects N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1078-0432.CCR-12-3654 ER -