TY - GEN AU - Castro,Elena AU - Goh,Chee AU - Olmos,David AU - Saunders,Ed AU - Leongamornlert,Daniel AU - Tymrakiewicz,Malgorzata AU - Mahmud,Nadiya AU - Dadaev,Tokhir AU - Govindasami,Koveela AU - Guy,Michelle AU - Sawyer,Emma AU - Wilkinson,Rosemary AU - Ardern-Jones,Audrey AU - Ellis,Steve AU - Frost,Debra AU - Peock,Susan AU - Evans,D Gareth AU - Tischkowitz,Marc AU - Cole,Trevor AU - Davidson,Rosemarie AU - Eccles,Diana AU - Brewer,Carole AU - Douglas,Fiona AU - Porteous,Mary E AU - Donaldson,Alan AU - Dorkins,Huw AU - Izatt,Louise AU - Cook,Jackie AU - Hodgson,Shirley AU - Kennedy,M John AU - Side,Lucy E AU - Eason,Jacqueline AU - Murray,Alex AU - Antoniou,Antonis C AU - Easton,Douglas F AU - Kote-Jarai,Zsofia AU - Eeles,Rosalind TI - Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer SN - 1527-7755 PY - 2013///0701 KW - Adult KW - Aged KW - Aged, 80 and over KW - Antineoplastic Agents, Hormonal KW - therapeutic use KW - Antineoplastic Combined Chemotherapy Protocols KW - BRCA1 Protein KW - genetics KW - BRCA2 Protein KW - Brachytherapy KW - Follow-Up Studies KW - Genetic Predisposition to Disease KW - Germ-Line Mutation KW - Heterozygote KW - Humans KW - Kaplan-Meier Estimate KW - Lymph Nodes KW - pathology KW - Lymphatic Metastasis KW - Male KW - Middle Aged KW - Neoplasm Grading KW - Neoplasm Staging KW - Nomograms KW - Palliative Care KW - methods KW - Phenotype KW - Predictive Value of Tests KW - Prognosis KW - Proportional Hazards Models KW - Prostatectomy KW - Prostatic Neoplasms KW - Radiotherapy, Adjuvant KW - Retrospective Studies KW - Risk Assessment KW - Risk Factors N1 - Publication Type: Journal Article UR - https://doi.org/10.1200/JCO.2012.43.1882 ER -