Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer. [electronic resource]
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology May 2013
- 1748-57 p. digital
Publication Type: Journal Article
1527-7755
10.1200/JCO.2012.43.1882 doi
Adult Aged Aged, 80 and over Antineoplastic Agents, Hormonal--therapeutic use Antineoplastic Combined Chemotherapy Protocols--therapeutic use BRCA1 Protein--genetics BRCA2 Protein--genetics Brachytherapy Follow-Up Studies Genetic Predisposition to Disease Germ-Line Mutation Heterozygote Humans Kaplan-Meier Estimate Lymph Nodes--pathology Lymphatic Metastasis Male Middle Aged Neoplasm Grading Neoplasm Staging Nomograms Palliative Care--methods Phenotype Predictive Value of Tests Prognosis Proportional Hazards Models Prostatectomy Prostatic Neoplasms--genetics Radiotherapy, Adjuvant Retrospective Studies Risk Assessment Risk Factors