TY - GEN AU - Takusagawa,Shin AU - Ushigome,Fumihiko AU - Nemoto,Hiroyuki AU - Takahashi,Yutaka AU - Li,Qun AU - Kerbusch,Virginie AU - Miyashita,Aiji AU - Iwatsubo,Takafumi AU - Usui,Takashi TI - Intestinal absorption mechanism of mirabegron, a potent and selective β₃-adrenoceptor agonist: involvement of human efflux and/or influx transport systems SN - 1543-8392 PY - 2013///1216 KW - ATP Binding Cassette Transporter, Subfamily B, Member 1 KW - metabolism KW - ATP Binding Cassette Transporter, Subfamily G, Member 2 KW - ATP-Binding Cassette Transporters KW - Acetanilides KW - pharmacokinetics KW - Adrenergic beta-3 Receptor Agonists KW - Animals KW - Biological Availability KW - Biological Transport, Active KW - Caco-2 Cells KW - Cell Membrane Permeability KW - Female KW - HEK293 Cells KW - Humans KW - Hydrogen-Ion Concentration KW - Intestinal Absorption KW - physiology KW - LLC-PK1 Cells KW - Neoplasm Proteins KW - Oocytes KW - Organic Anion Transporters KW - Peptide Transporter 1 KW - Recombinant Proteins KW - Swine KW - Symporters KW - Thiazoles KW - Urinary Bladder, Overactive KW - drug therapy KW - Xenopus laevis N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/mp300582s ER -