Zechariah, Anil

Hyperlipidemia attenuates vascular endothelial growth factor-induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells. [electronic resource] - Arteriosclerosis, thrombosis, and vascular biology Jul 2013 - 1561-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1524-4636

10.1161/ATVBAHA.112.300749 doi


Angiogenesis Inducing Agents--administration & dosage
Animals
Apolipoproteins E--deficiency
Autoradiography
Biomarkers--blood
Blood Flow Velocity
Blood-Brain Barrier--drug effects
Cadherins--metabolism
Capillaries--drug effects
Capillary Permeability--drug effects
Cerebrovascular Circulation--drug effects
Disease Models, Animal
Endothelial Cells--drug effects
Extracellular Matrix--metabolism
Humans
Hyperlipidemias--blood
Infusion Pumps, Implantable
Laser-Doppler Flowmetry
Lipids--blood
Luminescent Measurements
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Neovascularization, Physiologic--drug effects
Neuroprotective Agents--administration & dosage
Pericytes--drug effects
Stroke--blood
Time Factors
Vascular Endothelial Growth Factor A--administration & dosage