Zechariah, Anil
Hyperlipidemia attenuates vascular endothelial growth factor-induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells. [electronic resource]
- Arteriosclerosis, thrombosis, and vascular biology Jul 2013
- 1561-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1524-4636
10.1161/ATVBAHA.112.300749 doi
Angiogenesis Inducing Agents--administration & dosage
Animals
Apolipoproteins E--deficiency
Autoradiography
Biomarkers--blood
Blood Flow Velocity
Blood-Brain Barrier--drug effects
Cadherins--metabolism
Capillaries--drug effects
Capillary Permeability--drug effects
Cerebrovascular Circulation--drug effects
Disease Models, Animal
Endothelial Cells--drug effects
Extracellular Matrix--metabolism
Humans
Hyperlipidemias--blood
Infusion Pumps, Implantable
Laser-Doppler Flowmetry
Lipids--blood
Luminescent Measurements
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Neovascularization, Physiologic--drug effects
Neuroprotective Agents--administration & dosage
Pericytes--drug effects
Stroke--blood
Time Factors
Vascular Endothelial Growth Factor A--administration & dosage