Huang, Hsuan-Ying

ASS1 as a novel tumor suppressor gene in myxofibrosarcomas: aberrant loss via epigenetic DNA methylation confers aggressive phenotypes, negative prognostic impact, and therapeutic relevance. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Jun 2013 - 2861-72 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1557-3265

10.1158/1078-0432.CCR-12-2641 doi


Adult
Aged
Amino-Acid N-Acetyltransferase--biosynthesis
Animals
Argininosuccinate Synthase--deficiency
Cell Line, Tumor
Cell Movement--genetics
Cell Proliferation
Cell Survival--drug effects
Cluster Analysis
DNA Methylation
Female
Fibrosarcoma--drug therapy
G1 Phase Cell Cycle Checkpoints--genetics
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Gene Knockdown Techniques
Genes, Tumor Suppressor
Humans
Hydrolases--administration & dosage
Leiomyosarcoma--drug therapy
Male
Mice
Middle Aged
Neoplasm Grading
Neoplasm Invasiveness
Neoplasm Staging
Neovascularization, Pathologic--genetics
Phenotype
Polyethylene Glycols--administration & dosage
Prognosis
Xenograft Model Antitumor Assays