Phase I dose-escalation study of EZN-2208 (PEG-SN38), a novel conjugate of poly(ethylene) glycol and SN38, administered weekly in patients with advanced cancer. [electronic resource]
- Cancer chemotherapy and pharmacology Jun 2013
- 1499-506 p. digital
Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study
1432-0843
10.1007/s00280-013-2149-2 doi
Adult Aged Aged, 80 and over Antineoplastic Agents--administration & dosage Camptothecin--administration & dosage Data Interpretation, Statistical Dose-Response Relationship, Drug Drug Administration Schedule Female Humans Infusions, Intravenous Irinotecan Male Middle Aged Neoplasms--drug therapy Polyethylene Glycols--administration & dosage Prodrugs--administration & dosage Treatment Outcome