Kharitonenkov, Alexei
Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319. [electronic resource]
- PloS one 2013
- e58575 p. digital
Publication Type: Journal Article
1932-6203
10.1371/journal.pone.0058575 doi
3T3 Cells
Amino Acid Substitution
Animals
Cell Line
Drug Design
Fibroblast Growth Factors--chemistry
Gene Expression
Genetic Variation
Hep G2 Cells
Humans
Klotho Proteins
Male
Membrane Proteins--metabolism
Mice
Models, Molecular
Pichia--genetics
Protein Conformation
Protein Stability
Recombinant Proteins
Temperature