Kharitonenkov, Alexei

Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319. [electronic resource] - PloS one 2013 - e58575 p. digital

Publication Type: Journal Article

1932-6203

10.1371/journal.pone.0058575 doi


3T3 Cells
Amino Acid Substitution
Animals
Cell Line
Drug Design
Fibroblast Growth Factors--chemistry
Gene Expression
Genetic Variation
Hep G2 Cells
Humans
Klotho Proteins
Male
Membrane Proteins--metabolism
Mice
Models, Molecular
Pichia--genetics
Protein Conformation
Protein Stability
Recombinant Proteins
Temperature