Tran, Cassie M

Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity. [electronic resource] - The Journal of biological chemistry May 2013 - 12654-66 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1083-351X

10.1074/jbc.M112.448860 doi


Aggrecans--biosynthesis
Animals
Cell Hypoxia--genetics
Cell Line
Collagen Type II--biosynthesis
Connective Tissue Growth Factor--genetics
Gene Expression Regulation
Gene Knockdown Techniques
Humans
Hypoxia-Inducible Factor 1, alpha Subunit--genetics
Intervertebral Disc--metabolism
Mice
Mice, Mutant Strains
Rats