TY  - GEN
AU  - Rahman,Khondaker M
AU  - Jackson,Paul J M
AU  - James,Colin H
AU  - Basu,B Piku
AU  - Hartley,John A
AU  - de la Fuente,Maria
AU  - Schatzlein,Andreas
AU  - Robson,Mathew
AU  - Pedley,R Barbara
AU  - Pepper,Chris
AU  - Fox,Keith R
AU  - Howard,Philip W
AU  - Thurston,David E
TI  - GC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models
SN  - 1520-4804
PY  - 2013///0611
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Benzodiazepines
KW  - chemistry
KW  - Cell Line, Tumor
KW  - Disease Models, Animal
KW  - Drug Screening Assays, Antitumor
KW  - Fluorescence Resonance Energy Transfer
KW  - GC Rich Sequence
KW  - Humans
KW  - In Vitro Techniques
KW  - Magnetic Resonance Spectroscopy
KW  - Mice
KW  - Models, Molecular
KW  - Molecular Structure
KW  - NF-kappa B
KW  - antagonists & inhibitors
KW  - Spectrometry, Mass, Electrospray Ionization
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm301882a
ER  -