TY - GEN AU - Ramalho-Carvalho,João AU - Pires,Malini AU - Lisboa,Susana AU - Graça,Inês AU - Rocha,Patrícia AU - Barros-Silva,João Diogo AU - Savva-Bordalo,Joana AU - Maurício,Joaquina AU - Resende,Mário AU - Teixeira,Manuel R AU - Honavar,Mrinalini AU - Henrique,Rui AU - Jerónimo,Carmen TI - Altered expression of MGMT in high-grade gliomas results from the combined effect of epigenetic and genetic aberrations SN - 1932-6203 PY - 2013///0906 KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Chromosome Aberrations KW - DNA Copy Number Variations KW - DNA Methylation KW - DNA Modification Methylases KW - genetics KW - DNA Repair Enzymes KW - Epigenesis, Genetic KW - Gene Expression Regulation, Neoplastic KW - Glioma KW - Humans KW - Middle Aged KW - Neoplasm Grading KW - Prognosis KW - Promoter Regions, Genetic KW - RNA, Messenger KW - Tumor Suppressor Proteins KW - Young Adult N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0058206 ER -