TY - GEN AU - Cho,Jae-We AU - Il,Kwon-Jun AU - Lee,Kyu-Suk TI - Downregulation of type I collagen expression in silibinin-treated human skin fibroblasts by blocking the activation of Smad2/3-dependent signaling pathways: potential therapeutic use in the chemoprevention of keloids SN - 1791-244X PY - 2013///1029 KW - Cell Death KW - drug effects KW - Cell Nucleus KW - Cell Proliferation KW - Chemoprevention KW - Collagen Type I KW - genetics KW - Down-Regulation KW - Fibroblasts KW - Humans KW - Keloid KW - drug therapy KW - Matrix Metalloproteinases KW - metabolism KW - Phosphorylation KW - Promoter Regions, Genetic KW - Signal Transduction KW - Silybin KW - Silymarin KW - pharmacology KW - Skin KW - pathology KW - Smad Proteins KW - Smad2 Protein KW - Smad3 Protein KW - Tissue Inhibitor of Metalloproteinase-1 KW - Transforming Growth Factor beta1 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.3892/ijmm.2013.1303 ER -