TY - GEN AU - Hubbard,Basil P AU - Gomes,Ana P AU - Dai,Han AU - Li,Jun AU - Case,April W AU - Considine,Thomas AU - Riera,Thomas V AU - Lee,Jessica E AU - E,Sook Yen AU - Lamming,Dudley W AU - Pentelute,Bradley L AU - Schuman,Eli R AU - Stevens,Linda A AU - Ling,Alvin J Y AU - Armour,Sean M AU - Michan,Shaday AU - Zhao,Huizhen AU - Jiang,Yong AU - Sweitzer,Sharon M AU - Blum,Charles A AU - Disch,Jeremy S AU - Ng,Pui Yee AU - Howitz,Konrad T AU - Rolo,Anabela P AU - Hamuro,Yoshitomo AU - Moss,Joel AU - Perni,Robert B AU - Ellis,James L AU - Vlasuk,George P AU - Sinclair,David A TI - Evidence for a common mechanism of SIRT1 regulation by allosteric activators SN - 1095-9203 PY - 2013///0314 KW - Allosteric Regulation KW - Amino Acid Motifs KW - Amino Acid Sequence KW - Amino Acid Substitution KW - Animals KW - Cells, Cultured KW - Enzyme Activation KW - Forkhead Box Protein O3 KW - Forkhead Transcription Factors KW - chemistry KW - Glutamic Acid KW - Heterocyclic Compounds, 4 or More Rings KW - Humans KW - Hydrophobic and Hydrophilic Interactions KW - Mice KW - Molecular Sequence Data KW - Myoblasts KW - drug effects KW - Protein Structure, Tertiary KW - Resveratrol KW - Sirtuin 1 KW - Stilbenes KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/science.1231097 ER -