TY - GEN AU - Lamberts,Jennifer T AU - Smith,Chelsea E AU - Li,Ming-Hua AU - Ingram,Susan L AU - Neubig,Richard R AU - Traynor,John R TI - Differential control of opioid antinociception to thermal stimuli in a knock-in mouse expressing regulator of G-protein signaling-insensitive Gαo protein SN - 1529-2401 PY - 2013///0426 KW - Analgesics, Opioid KW - pharmacology KW - Animals KW - Brain KW - drug effects KW - Diprenorphine KW - pharmacokinetics KW - Dose-Response Relationship, Drug KW - Electric Stimulation KW - Enkephalin, Ala(2)-MePhe(4)-Gly(5)- KW - Excitatory Amino Acid Antagonists KW - Female KW - GABA Antagonists KW - GTP-Binding Protein alpha Subunits, Gi-Go KW - metabolism KW - Gene Expression Regulation KW - Guanosine 5'-O-(3-Thiotriphosphate) KW - Hot Temperature KW - adverse effects KW - Humans KW - Hyperalgesia KW - drug therapy KW - Inhibitory Postsynaptic Potentials KW - Isotopes KW - Male KW - Methadone KW - Mice KW - Mice, Transgenic KW - Morphine KW - Mutation KW - Naloxone KW - Naltrexone KW - Narcotic Antagonists KW - Neurons KW - Oligopeptides KW - Pain Measurement KW - Patch-Clamp Techniques KW - Pertussis Toxin KW - Protein Binding KW - RGS Proteins KW - genetics KW - Reaction Time KW - Signal Transduction KW - Spinal Cord KW - gamma-Aminobutyric Acid N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1523/JNEUROSCI.5470-12.2013 ER -