Yu, Jianhua

Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia. [electronic resource] - PloS one 2013 - e55934 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0055934 doi


Animals
Antineoplastic Agents--pharmacology
Caspases--metabolism
Cell Line, Tumor
Cell Proliferation--drug effects
Curcumin--pharmacology
DNA (Cytosine-5-)-Methyltransferase 1
DNA (Cytosine-5-)-Methyltransferases--genetics
Down-Regulation--drug effects
Female
G1 Phase Cell Cycle Checkpoints--drug effects
Humans
Leukemia, Myeloid, Acute--drug therapy
Mice
Mice, Nude
Promoter Regions, Genetic--drug effects
Sp1 Transcription Factor--genetics
Transcription Factor RelA--genetics
Tumor Cells, Cultured