TY - GEN AU - Hassan,Khaled A AU - Wang,Luo AU - Korkaya,Hasan AU - Chen,Guoan AU - Maillard,Ivan AU - Beer,David G AU - Kalemkerian,Gregory P AU - Wicha,Max S TI - Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma SN - 1557-3265 PY - 2013///1111 KW - Adenocarcinoma KW - drug therapy KW - Animals KW - Apoptosis KW - drug effects KW - Basic Helix-Loop-Helix Transcription Factors KW - genetics KW - Cell Cycle KW - Cell Line, Tumor KW - Cyclic S-Oxides KW - pharmacology KW - Flow Cytometry KW - Gene Expression Regulation, Neoplastic KW - Green Fluorescent Proteins KW - Homeodomain Proteins KW - Humans KW - Immunohistochemistry KW - Kaplan-Meier Estimate KW - Lung Neoplasms KW - Mice KW - Mice, Inbred NOD KW - Mice, Nude KW - Mice, SCID KW - Multivariate Analysis KW - Neoplastic Stem Cells KW - Protein Isoforms KW - antagonists & inhibitors KW - Receptors, Notch KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - Thiadiazoles KW - Transcription Factor HES-1 KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1078-0432.CCR-12-0370 ER -