Hassan, Khaled A

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Apr 2013 - 1972-80 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1557-3265

10.1158/1078-0432.CCR-12-0370 doi


Adenocarcinoma--drug therapy
Animals
Apoptosis--drug effects
Basic Helix-Loop-Helix Transcription Factors--genetics
Cell Cycle--drug effects
Cell Line, Tumor
Cyclic S-Oxides--pharmacology
Flow Cytometry
Gene Expression Regulation, Neoplastic
Green Fluorescent Proteins--genetics
Homeodomain Proteins--genetics
Humans
Immunohistochemistry
Kaplan-Meier Estimate
Lung Neoplasms--drug therapy
Mice
Mice, Inbred NOD
Mice, Nude
Mice, SCID
Multivariate Analysis
Neoplastic Stem Cells--drug effects
Protein Isoforms--antagonists & inhibitors
Receptors, Notch--antagonists & inhibitors
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--drug effects
Thiadiazoles--pharmacology
Transcription Factor HES-1
Xenograft Model Antitumor Assays