TY  - GEN
AU  - Reuss,David E
AU  - Mucha,Jana
AU  - Hagenlocher,Christian
AU  - Ehemann,Volker
AU  - Kluwe,Lan
AU  - Mautner,Victor
AU  - von Deimling,Andreas
TI  - Sensitivity of malignant peripheral nerve sheath tumor cells to TRAIL is augmented by loss of NF1 through modulation of MYC/MAD and is potentiated by curcumin through induction of ROS
SN  - 1932-6203
PY  - 2013///0806
KW  - Acetylcysteine
KW  - pharmacology
KW  - Antineoplastic Agents, Phytogenic
KW  - Apoptosis
KW  - drug effects
KW  - Cell Cycle Proteins
KW  - genetics
KW  - Cell Line, Tumor
KW  - Curcumin
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - MAP Kinase Signaling System
KW  - Nerve Sheath Neoplasms
KW  - complications
KW  - Neurofibromatosis 1
KW  - Neurofibromin 1
KW  - antagonists & inhibitors
KW  - Nuclear Proteins
KW  - Phosphatidylinositol 3-Kinases
KW  - Protein Structure, Tertiary
KW  - Proto-Oncogene Proteins c-akt
KW  - Proto-Oncogene Proteins c-myc
KW  - Reactive Oxygen Species
KW  - Receptors, TNF-Related Apoptosis-Inducing Ligand
KW  - Schwann Cells
KW  - Signal Transduction
KW  - TNF-Related Apoptosis-Inducing Ligand
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0057152
ER  -