Reuss, David E <br/><br/>
Sensitivity of malignant peripheral nerve sheath tumor cells to TRAIL is augmented by loss of NF1 through modulation of MYC/MAD and is potentiated by curcumin through induction of ROS.  [electronic resource] 

 -  PloS one  2013 
 - e57152 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0057152  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylcysteine--pharmacology<br/>Antineoplastic Agents, Phytogenic--pharmacology<br/>Apoptosis--drug effects<br/>Cell Cycle Proteins--genetics<br/>Cell Line, Tumor<br/>Curcumin--pharmacology<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Humans<br/>MAP Kinase Signaling System--drug effects<br/>Nerve Sheath Neoplasms--complications<br/>Neurofibromatosis 1--complications<br/>Neurofibromin 1--antagonists & inhibitors<br/>Nuclear Proteins--genetics<br/>Phosphatidylinositol 3-Kinases--genetics<br/>Protein Structure, Tertiary<br/>Proto-Oncogene Proteins c-akt--genetics<br/>Proto-Oncogene Proteins c-myc--genetics<br/>Reactive Oxygen Species--antagonists & inhibitors<br/>Receptors, TNF-Related Apoptosis-Inducing Ligand--genetics<br/>Schwann Cells--drug effects<br/>Signal Transduction--drug effects<br/>TNF-Related Apoptosis-Inducing Ligand--genetics