TY - GEN AU - Zhu,Rui AU - Zheng,Yanan AU - Putnam,Wendy S AU - Visich,Jennifer AU - Eisner,Mark D AU - Matthews,John G AU - Rosen,Karin E AU - D'Argenio,David Z TI - Population-based efficacy modeling of omalizumab in patients with severe allergic asthma inadequately controlled with standard therapy SN - 1550-7416 PY - 2013///1022 KW - Adolescent KW - Adult KW - Aged KW - Anti-Asthmatic Agents KW - administration & dosage KW - Antibodies, Anti-Idiotypic KW - Antibodies, Monoclonal, Humanized KW - Asthma KW - diagnosis KW - Biomarkers KW - blood KW - Breath Tests KW - Child KW - Computer Simulation KW - Double-Blind Method KW - Drug Administration Schedule KW - Female KW - Forced Expiratory Volume KW - Humans KW - Immunoglobulin E KW - Lung KW - drug effects KW - Male KW - Middle Aged KW - Models, Biological KW - Monte Carlo Method KW - Nitric Oxide KW - metabolism KW - Omalizumab KW - Prospective Studies KW - Spirometry KW - Time Factors KW - Treatment Outcome KW - Young Adult N1 - Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial UR - https://doi.org/10.1208/s12248-013-9463-9 ER -