Odagiri, Takashi <br/><br/>
Design, synthesis, and biological evaluations of novel 7-[7-amino-7-methyl-5-azaspiro[2.4]heptan-5-yl]-8-methoxyquinolines with potent antibacterial activity against respiratory pathogens.  [electronic resource] 

 -  Journal of medicinal chemistry  Mar 2013 
 - 1974-83 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm301650g  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anti-Bacterial Agents--chemical synthesis<br/>Drug Design<br/>Fluoroquinolones--chemical synthesis<br/>Haemophilus influenzae--drug effects<br/>Male<br/>Mice<br/>Microbial Sensitivity Tests<br/>Quinolones--chemical synthesis<br/>Rats<br/>Respiratory Tract Infections--drug therapy<br/>Spiro Compounds--chemical synthesis<br/>Staphylococcus aureus--drug effects<br/>Streptococcus pneumoniae--drug effects