TY - GEN AU - Choe,Jung-Yoon AU - Park,Ki-Yeun AU - Park,Sung-Hoon AU - Lee,Sang-Il AU - Kim,Seong-Kyu TI - Regulatory effect of calcineurin inhibitor, tacrolimus, on IL-6/sIL-6R-mediated RANKL expression through JAK2-STAT3-SOCS3 signaling pathway in fibroblast-like synoviocytes SN - 1478-6362 PY - 2015///0512 KW - Animals KW - Arthritis, Experimental KW - drug therapy KW - Arthritis, Rheumatoid KW - immunology KW - Blotting, Western KW - Calcineurin Inhibitors KW - pharmacology KW - Cells, Cultured KW - Enzyme-Linked Immunosorbent Assay KW - Female KW - Fibroblasts KW - drug effects KW - Humans KW - Interleukin-6 KW - Janus Kinase 2 KW - metabolism KW - Male KW - Mesenchymal Stem Cells KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - RANK Ligand KW - biosynthesis KW - Real-Time Polymerase Chain Reaction KW - STAT3 Transcription Factor KW - Signal Transduction KW - Suppressor of Cytokine Signaling 3 Protein KW - Suppressor of Cytokine Signaling Proteins KW - Synovial Membrane KW - cytology KW - Tacrolimus N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/ar4162 ER -