TY  - GEN
AU  - Barbara,Joanna E
AU  - Kazmi,Faraz
AU  - Parkinson,Andrew
AU  - Buckley,David B
TI  - Metabolism-dependent inhibition of CYP3A4 by lapatinib: evidence for formation of a metabolic intermediate complex with a nitroso/oxime metabolite formed via a nitrone intermediate
SN  - 1521-009X
PY  - 2013///1029
KW  - Chromatography, Liquid
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 CYP3A Inhibitors
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Humans
KW  - Lapatinib
KW  - Mass Spectrometry
KW  - Microsomes, Liver
KW  - metabolism
KW  - Nitrogen Oxides
KW  - Oximes
KW  - Quinazolines
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1124/dmd.113.051151
ER  -