Park, Jin Joo <br/><br/>
CYP3A4 genetic status may be associated with increased vulnerability to the inhibitory effect of calcium-channel blockers on clopidogrel.  [electronic resource] 

 -  Circulation journal : official journal of the Japanese Circulation Society  2013 
 - 1289-96 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1347-4820 
<br/><br/><label>Standard No.: </label>10.1253/circj.cj-12-0682  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aged<br/>Blood Platelets--drug effects<br/>Calcium Channel Blockers--therapeutic use<br/>Chi-Square Distribution<br/>Clopidogrel<br/>Cytochrome P-450 CYP3A--genetics<br/>Cytochrome P-450 CYP3A Inhibitors<br/>Drug Interactions<br/>Enzyme Inhibitors--therapeutic use<br/>Female<br/>Gene Frequency<br/>Genotype<br/>Humans<br/>Linear Models<br/>Logistic Models<br/>Male<br/>Middle Aged<br/>Multivariate Analysis<br/>Odds Ratio<br/>Pharmacogenetics<br/>Phenotype<br/>Platelet Aggregation--drug effects<br/>Platelet Aggregation Inhibitors--administration & dosage<br/>Platelet Function Tests<br/>Prospective Studies<br/>Purinergic P2Y Receptor Antagonists--administration & dosage<br/>Receptors, Purinergic P2Y12--blood<br/>Risk Factors<br/>Ticlopidine--administration & dosage