TY - GEN AU - Singh,Rajvir AU - De Aguiar,Renata Belfort AU - Naik,Sarita AU - Mani,Sheida AU - Ostadsharif,Kamal AU - Wencker,Detlef AU - Sotoudeh,Masoud AU - Malekzadeh,Reza AU - Sherwin,Robert S AU - Mani,Arya TI - LRP6 enhances glucose metabolism by promoting TCF7L2-dependent insulin receptor expression and IGF receptor stabilization in humans SN - 1932-7420 PY - 2013///0920 KW - 3T3-L1 Cells KW - Animals KW - Cells, Cultured KW - Fibroblasts KW - drug effects KW - Gene Knockdown Techniques KW - Glucose KW - metabolism KW - Glucose Tolerance Test KW - Humans KW - Insulin KW - pharmacology KW - Insulin Receptor Substrate Proteins KW - Low Density Lipoprotein Receptor-Related Protein-6 KW - genetics KW - Mechanistic Target of Rapamycin Complex 1 KW - Mice KW - Models, Biological KW - Multiprotein Complexes KW - Muscle, Skeletal KW - Mutation KW - Phosphoserine KW - Protein Stability KW - Receptor, IGF Type 1 KW - Receptor, Insulin KW - Skin KW - cytology KW - TOR Serine-Threonine Kinases KW - Transcription Factor 7-Like 2 Protein KW - Transcription, Genetic KW - Wnt Signaling Pathway N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1016/j.cmet.2013.01.009 ER -