TY - GEN AU - Datta,Debajyoti AU - McClendon,Christopher L AU - Jacobson,Matthew P AU - Wells,James A TI - Substrate and inhibitor-induced dimerization and cooperativity in caspase-1 but not caspase-3 SN - 1083-351X PY - 2013///0531 KW - Allosteric Site KW - Amino Acid Chloromethyl Ketones KW - chemistry KW - Area Under Curve KW - Biophysics KW - methods KW - Caspase 1 KW - metabolism KW - Caspase 3 KW - Caspases KW - Catalytic Domain KW - Dimerization KW - Enzyme Inhibitors KW - pharmacology KW - Gene Expression Regulation, Enzymologic KW - Humans KW - Inflammation KW - Kinetics KW - Models, Molecular KW - Molecular Conformation KW - Protein Binding KW - Protein Conformation KW - Substrate Specificity KW - Ultracentrifugation N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1074/jbc.M112.426460 ER -