Pastore, Nunzia <br/><br/>
Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-anti-trypsin deficiency.  [electronic resource] 

 -  EMBO molecular medicine  Mar 2013 
 - 397-412 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1757-4684 
<br/><br/><label>Standard No.: </label>10.1002/emmm.201202046  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis<br/>Autophagy--genetics<br/>Autophagy-Related Protein 7<br/>Basic Helix-Loop-Helix Leucine Zipper Transcription Factors--genetics<br/>Disease Models, Animal<br/>Gene Transfer Techniques<br/>Genetic Predisposition to Disease<br/>Genetic Therapy--methods<br/>HeLa Cells<br/>Humans<br/>Interleukin-6--metabolism<br/>Liver--enzymology<br/>Liver Cirrhosis--genetics<br/>Lysosomes--metabolism<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>Mice, Transgenic<br/>Microtubule-Associated Proteins--deficiency<br/>Mutation, Missense<br/>NF-kappa B--metabolism<br/>Papio<br/>Phenotype<br/>Time Factors<br/>Transfection<br/>alpha 1-Antitrypsin--genetics<br/>alpha 1-Antitrypsin Deficiency--complications