Li, Yuanyuan
Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer. [electronic resource]
- Molecular cancer Feb 2013
- 9 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
ISSN: 1476-4598
Standard No.: 10.1186/1476-4598-12-9 doi
Subjects--Topical Terms: Animals Anticarcinogenic Agents--administration & dosage Antineoplastic Agents, Hormonal--administration & dosage Azacitidine--analogs & derivatives Breast Neoplasms--drug therapy Cell Line, Tumor Cell Proliferation--drug effects Cell Survival--drug effects DNA (Cytosine-5-)-Methyltransferase 1 DNA (Cytosine-5-)-Methyltransferases--metabolism Decitabine Drug Resistance, Neoplasm--drug effects Drug Synergism Epigenesis, Genetic--drug effects Estradiol--pharmacology Estrogen Receptor alpha--genetics Female Gene Expression--drug effects Genistein--administration & dosage Histone Deacetylase 1--metabolism Histone Deacetylase Inhibitors--pharmacology Histones--metabolism Humans Hydroxamic Acids--pharmacology Mice Mice, Nude Mice, Transgenic Proliferating Cell Nuclear Antigen--metabolism Promoter Regions, Genetic Tamoxifen--administration & dosage Tumor Burden--drug effects Xenograft Model Antitumor Assays