Walsby, Elisabeth J <br/><br/>
The HSP90 inhibitor NVP-AUY922-AG inhibits the PI3K and IKK signalling pathways and synergizes with cytarabine in acute myeloid leukaemia cells.  [electronic resource] 

 -  British journal of haematology  Apr 2013 
 - 57-67 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1365-2141 
<br/><br/><label>Standard No.: </label>10.1111/bjh.12215  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aged<br/>Aged, 80 and over<br/>Annexin A5--metabolism<br/>Antineoplastic Agents--administration & dosage<br/>Antineoplastic Combined Chemotherapy Protocols--administration & dosage<br/>Apoptosis--drug effects<br/>Caspase 3--metabolism<br/>Cytarabine--administration & dosage<br/>Dose-Response Relationship, Drug<br/>Drug Screening Assays, Antitumor--methods<br/>Drug Synergism<br/>Female<br/>HSP90 Heat-Shock Proteins--antagonists & inhibitors<br/>Humans<br/>I-kappa B Kinase--drug effects<br/>Isoxazoles--administration & dosage<br/>Leukemia, Myeloid, Acute--drug therapy<br/>Male<br/>Middle Aged<br/>Neoplasm Proteins--antagonists & inhibitors<br/>Phosphatidylinositol 3-Kinases--drug effects<br/>Resorcinols--administration & dosage<br/>Signal Transduction--drug effects<br/>Tumor Cells, Cultured--drug effects<br/>Young Adult