TY - GEN AU - Meng,Jingjing AU - Yu,Haidong AU - Ma,Jing AU - Wang,Jinghua AU - Banerjee,Santanu AU - Charboneau,Rick AU - Barke,Roderick A AU - Roy,Sabita TI - Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TLR-dependent manner SN - 1932-6203 PY - 2013///0724 KW - Analgesics, Opioid KW - pharmacology KW - Animals KW - Azepines KW - Bacterial Translocation KW - drug effects KW - Blotting, Western KW - Cell Line KW - Colon KW - Epithelium KW - Ileum KW - Intestinal Mucosa KW - metabolism KW - Intestines KW - Liver KW - Lymph Nodes KW - Mesentery KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Microscopy, Fluorescence KW - Morphine KW - Myosin-Light-Chain Kinase KW - antagonists & inhibitors KW - Naphthalenes KW - Receptors, Opioid, mu KW - genetics KW - Reverse Transcriptase Polymerase Chain Reaction KW - Tight Junctions KW - Toll-Like Receptor 2 KW - Toll-Like Receptor 4 KW - Zonula Occludens-1 Protein N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1371/journal.pone.0054040 ER -