Albanese, C <br/><br/>
Anti-tumour efficacy on glioma models of PHA-848125, a multi-kinase inhibitor able to cross the blood-brain barrier.  [electronic resource] 

 -  British journal of pharmacology  May 2013 
 - 156-66 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1476-5381 
<br/><br/><label>Standard No.: </label>10.1111/bph.12112  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--pharmacokinetics<br/>Blood-Brain Barrier--metabolism<br/>Brain Neoplasms--drug therapy<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Combined Modality Therapy<br/>Dacarbazine--analogs & derivatives<br/>Drug Synergism<br/>Glioma--drug therapy<br/>Humans<br/>Male<br/>Mice<br/>Mice, Inbred BALB C<br/>Mice, Nude<br/>Protein Kinase Inhibitors--pharmacokinetics<br/>Pyrazoles--pharmacokinetics<br/>Quinazolines--pharmacokinetics<br/>Rats<br/>Rats, Sprague-Dawley<br/>Signal Transduction--drug effects<br/>Temozolomide<br/>Xenograft Model Antitumor Assays