BMP induces cochlin expression to facilitate self-renewal and suppress neural differentiation of mouse embryonic stem cells. [electronic resource]
- The Journal of biological chemistry Mar 2013
- 8053-8060 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1083-351X
10.1074/jbc.M112.433995 doi
Animals Base Sequence Binding Sites Bone Morphogenetic Protein 4--physiology Cell Differentiation Cell Proliferation Cells, Cultured Consensus Sequence Embryonic Stem Cells--metabolism Enzyme Activation Extracellular Matrix Proteins--genetics Extracellular Signal-Regulated MAP Kinases--metabolism Gene Knockdown Techniques Humans Mice Neurons--metabolism Promoter Regions, Genetic RNA, Small Interfering--genetics Signal Transduction Smad Proteins--metabolism Transcriptional Activation Up-Regulation