TY  - GEN
AU  - Iyengar,Sunil
AU  - Clear,Andrew
AU  - Bödör,Csaba
AU  - Maharaj,Lenushka
AU  - Lee,Abigail
AU  - Calaminici,Maria
AU  - Matthews,Janet
AU  - Iqbal,Sameena
AU  - Auer,Rebecca
AU  - Gribben,John
AU  - Joel,Simon
TI  - P110α-mediated constitutive PI3K signaling limits the efficacy of p110δ-selective inhibition in mantle cell lymphoma, particularly with multiple relapse
SN  - 1528-0020
PY  - 2013///0516
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - pharmacology
KW  - Cell Line, Tumor
KW  - Class I Phosphatidylinositol 3-Kinases
KW  - DNA Mutational Analysis
KW  - Drug Resistance, Neoplasm
KW  - genetics
KW  - Gene Expression Regulation, Enzymologic
KW  - physiology
KW  - Gene Expression Regulation, Neoplastic
KW  - drug effects
KW  - Humans
KW  - Lymphoma, Mantle-Cell
KW  - drug therapy
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Protein Kinase Inhibitors
KW  - administration & dosage
KW  - Purines
KW  - Quinazolinones
KW  - Recurrence
KW  - Signal Transduction
KW  - Substrate Specificity
KW  - Treatment Outcome
N1  - Publication Type: Evaluation Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1182/blood-2012-10-460832
ER  -