Synthesis of long-circulating, backbone degradable HPMA copolymer-doxorubicin conjugates and evaluation of molecular-weight-dependent antitumor efficacy. [electronic resource]
- Macromolecular bioscience Feb 2013
- 155-60 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1616-5195
10.1002/mabi.201200353 doi
Animals Antibiotics, Antineoplastic--chemistry Body Weight--drug effects Doxorubicin--analogs & derivatives Drug Carriers--chemistry Female Humans Mice Mice, Nude Molecular Weight Ovarian Neoplasms--drug therapy Polymethacrylic Acids--chemical synthesis Structure-Activity Relationship Xenograft Model Antitumor Assays