Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin. [electronic resource]
- Oncology reports Apr 2013
- 1333-42 p. digital
Publication Type: Journal Article
1791-2431
10.3892/or.2013.2242 doi
Apoptosis--drug effects Autophagy--drug effects Brain Neoplasms--drug therapy Cell Line, Tumor Down-Regulation Gene Expression Regulation, Neoplastic--drug effects Glioma--drug therapy Harmine--analogs & derivatives Humans Inhibitor of Apoptosis Proteins--genetics Proto-Oncogene Proteins c-akt--genetics RNA, Small Interfering Signal Transduction Survivin TOR Serine-Threonine Kinases--metabolism