TY - GEN AU - D'Assoro,A B AU - Liu,T AU - Quatraro,C AU - Amato,A AU - Opyrchal,M AU - Leontovich,A AU - Ikeda,Y AU - Ohmine,S AU - Lingle,W AU - Suman,V AU - Ecsedy,J AU - Iankov,I AU - Di Leonardo,A AU - Ayers-Inglers,J AU - Degnim,A AU - Billadeau,D AU - McCubrey,J AU - Ingle,J AU - Salisbury,J L AU - Galanis,E TI - The mitotic kinase Aurora--a promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα(+) breast cancer cells SN - 1476-5594 PY - 2014///0401 KW - Active Transport, Cell Nucleus KW - Animals KW - Aurora Kinase A KW - antagonists & inhibitors KW - Breast Neoplasms KW - enzymology KW - CD24 Antigen KW - genetics KW - Cell Line, Tumor KW - Cell Movement KW - Epithelial-Mesenchymal Transition KW - Estrogen Receptor alpha KW - biosynthesis KW - Female KW - Gene Expression Regulation, Neoplastic KW - Humans KW - MAP Kinase Signaling System KW - MCF-7 Cells KW - Mice KW - Mice, Nude KW - Neoplasm Metastasis KW - Neoplasm Transplantation KW - Neoplastic Stem Cells KW - cytology KW - Phosphorylation KW - Proto-Oncogene Proteins c-raf KW - metabolism KW - RNA Interference KW - RNA, Small Interfering KW - Receptor, ErbB-2 KW - SOXB1 Transcription Factors KW - Smad5 Protein KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/onc.2012.628 ER -