Gangjee, Aleem <br/><br/>
Synthesis of N(4)-(substituted phenyl)-N(4)-alkyl/desalkyl-9H-pyrimido[4,5-b]indole-2,4-diamines and identification of new microtubule disrupting compounds that are effective against multidrug resistant cells.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  Feb 2013 
 - 891-902 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3391 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2012.12.010  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aniline Compounds--chemistry<br/>Binding Sites<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Colchicine--chemistry<br/>Cyclization<br/>Cyclohexanones--chemistry<br/>Diamines--chemical synthesis<br/>Drug Resistance, Neoplasm--drug effects<br/>Drug Screening Assays, Antitumor<br/>Humans<br/>Indoles--chemistry<br/>Microtubules--chemistry<br/>Molecular Docking Simulation<br/>Oxidation-Reduction<br/>Protein Binding<br/>Protein Structure, Tertiary<br/>Pyrimidines--chemistry<br/>Tubulin Modulators--chemical synthesis