TY  - GEN
AU  - Strushkevich,Natallia
AU  - Gilep,Andrei A
AU  - Shen,Limin
AU  - Arrowsmith,Cheryl H
AU  - Edwards,Aled M
AU  - Usanov,Sergey A
AU  - Park,Hee-Won
TI  - Structural insights into aldosterone synthase substrate specificity and targeted inhibition
SN  - 1944-9917
PY  - 2013///0708
KW  - Aldosterone
KW  - biosynthesis
KW  - Blood Pressure
KW  - Catalysis
KW  - Crystallography, X-Ray
KW  - Cytochrome P-450 CYP11B2
KW  - antagonists & inhibitors
KW  - Desoxycorticosterone
KW  - chemistry
KW  - Fadrozole
KW  - Humans
KW  - Hypertension
KW  - Models, Molecular
KW  - Protein Structure, Tertiary
KW  - Renin-Angiotensin System
KW  - Steroid 11-beta-Hydroxylase
KW  - metabolism
KW  - Substrate Specificity
KW  - Water-Electrolyte Balance
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1210/me.2012-1287
ER  -