TY  - GEN
AU  - Dai,ChuanYun
AU  - Fu,Ya
AU  - Chen,ShaoCheng
AU  - Li,Biao
AU  - Yao,Bo
AU  - Liu,WanHong
AU  - Zhu,LiQing
AU  - Chen,Nan
AU  - Chen,Ji
AU  - Zhang,Qiang
TI  - Preparation and evaluation of a new releasable PEGylated tumor necrosis factor-α (TNF-α) conjugate for therapeutic application
SN  - 1869-1889
PY  - 2013///0701
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemistry
KW  - Cathepsin B
KW  - antagonists & inhibitors
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - drug effects
KW  - Dipeptides
KW  - Dose-Response Relationship, Drug
KW  - Drug Compounding
KW  - Drug Evaluation, Preclinical
KW  - Glycopeptides
KW  - pharmacology
KW  - Humans
KW  - Hydrogen-Ion Concentration
KW  - Leucine
KW  - analogs & derivatives
KW  - Lysosomes
KW  - enzymology
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Neoplasms, Experimental
KW  - drug therapy
KW  - Pepstatins
KW  - Polyethylene Glycols
KW  - Protease Inhibitors
KW  - Rats
KW  - Time Factors
KW  - Tumor Burden
KW  - Tumor Necrosis Factor-alpha
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s11427-012-4431-7
ER  -