TY  - GEN
AU  - Olaru,Florina
AU  - Wang,Xu-Ping
AU  - Luo,Wentian
AU  - Ge,Linna
AU  - Miner,Jeffrey H
AU  - Kleinau,Sandra
AU  - Geiger,Xochiquetzal J
AU  - Wasiluk,Andrew
AU  - Heidet,Laurence
AU  - Kitching,A Richard
AU  - Borza,Dorin-Bogdan
TI  - Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers
SN  - 1550-6606
PY  - 2013///0328
KW  - Animals
KW  - Anti-Glomerular Basement Membrane Disease
KW  - genetics
KW  - Antibody Specificity
KW  - Autoantibodies
KW  - biosynthesis
KW  - Autoantigens
KW  - immunology
KW  - Collagen Type IV
KW  - Disease Models, Animal
KW  - Epitopes
KW  - Female
KW  - HEK293 Cells
KW  - Humans
KW  - Immune Tolerance
KW  - Immunoglobulin G
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Inbred DBA
KW  - Mice, Knockout
KW  - Mice, Transgenic
KW  - Proteolysis
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.4049/jimmunol.1202204
ER  -