Olaru, Florina

Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Feb 2013 - 1424-32 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1550-6606

10.4049/jimmunol.1202204 doi


Animals
Anti-Glomerular Basement Membrane Disease--genetics
Antibody Specificity
Autoantibodies--biosynthesis
Autoantigens--immunology
Collagen Type IV--immunology
Disease Models, Animal
Epitopes--immunology
Female
HEK293 Cells
Humans
Immune Tolerance--genetics
Immunoglobulin G--biosynthesis
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Mice, Knockout
Mice, Transgenic
Proteolysis