TY - GEN AU - Loi,Sherene AU - Michiels,Stefan AU - Baselga,Jose AU - Bartlett,John M S AU - Singhal,Sandeep K AU - Sabine,Vicky S AU - Sims,Andrew H AU - Sahmoud,Tarek AU - Dixon,J Michael AU - Piccart,Martine J AU - Sotiriou,Christos TI - PIK3CA genotype and a PIK3CA mutation-related gene signature and response to everolimus and letrozole in estrogen receptor positive breast cancer SN - 1932-6203 PY - 2013///0820 KW - Aged KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Breast Neoplasms KW - genetics KW - Cell Proliferation KW - Class I Phosphatidylinositol 3-Kinases KW - Everolimus KW - Female KW - Gene Expression Regulation, Neoplastic KW - Genotype KW - Humans KW - Letrozole KW - Middle Aged KW - Mutation KW - Nitriles KW - administration & dosage KW - Phosphatidylinositol 3-Kinases KW - Receptors, Estrogen KW - metabolism KW - Sirolimus KW - TOR Serine-Threonine Kinases KW - Triazoles N1 - Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0053292 ER -